How to take medication for trigeminal neuralgia and precautions

  There are many treatments for trigeminal neuralgia, the first is medication. Here, the drugs that can control trigeminal neuralgia are briefly introduced to you: 1. Carbamazepine tablets This is the most classic drug for trigeminal neuralgia, it is actually mainly used as an anti-epileptic drug, and later it was found that he has good effect in treating trigeminal neuralgia. It can block the Na ion and calcium ion channels in the cell membrane, inhibit the occurrence and spread of abnormal high-frequency nerve discharges, and enhance the activity of the central noradrenergic nerves. Achieve the effect of pain relief. However, carbamazepine has the problem of causing dizziness and abnormal liver function. So, take this drug at first from one a day, a small dose, to later when the effect is not good, and then gradually increase the amount of elderly people up to three a day, pay attention to every half month to check liver function; 2, oxcarbazepine tablets Oxcarbazepine is a modified carbamazepine of the same type of drugs, the role of the incentive is similar, can also be treated trigeminal neuralgia. Compared to carbamazepine, oxcarbazepine is not necessarily better than carbamazepine in treating primary trigeminal neuralgia. But there are fewer adverse reactions.  3, Pregabalin capsule Pregabalin is a new γ-aminobutyric acid (GABA) receptor agonist, can block voltage-dependent calcium channels, reduce the release of neurotransmitters, mainly for the treatment of peripheral neuralgia and adjuvant treatment of limited partial seizures. It has been shown to provide some relief for pain such as postherpetic neuralgia and fibromyalgia syndrome; however, it is not as effective as carbamazepine. For patients for whom carbamazepine treatment has failed, pregabalin can be used. It is also recommended to start with a small dose and increase the dose as slowly as possible.  4. Gabapentin is a relatively new drug. Its mode of action in the treatment of neuropathic pain is still unclear. The mechanism of gabapentin’s anti-abnormal pain effect includes: a central effect through increased inhibitory input to the GABA-mediated pathway; antagonism of NMDA receptors; and antagonism of calcium channels in the CNS and inhibition of peripheral nerve conduction. It, like pregabalin, is only a second-line drug for the treatment of trigeminal neuralgia, and gabapentin can be used for patients who are not well controlled by carbamazepine.