Aminoglycoside antibiotics are commonly used, such as Gentamicin, Streptomycin, Amikacin, Etimicin and so on. 1. Gentamicin: this drug mainly treats infectious diseases caused by sensitive gram-negative bacilli, such as Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae. 2. Streptomycin: the drug has relatively weak therapeutic effect on the above mentioned gram-negative bacilli, mainly used in the treatment of tuberculosis, but also can be used in the treatment of brucellosis, and penicillin can be used in combination to treat infective endocarditis caused by Streptococcus agalactiae and other germs. 3. Amikacin: the drug is relatively stable to aminoglycoside passivation enzyme, for gentamicin-resistant negative bacilli the use of this product may still be effective; can also be applied to methicillin-sensitive staphylococcus aureus treatment, but generally need to be combined with drugs. In addition, it can also be applied to the treatment of tuberculosis. 4. Etimicin: this product is mainly used in the treatment of sensitive gram-negative bacilli, renal insufficiency patients need to be used with caution, such as must be used need to reduce the amount of disease, close detection of renal function and other indicators. Aminoglycoside antibiotics may cause adverse reactions, the more common adverse reactions are kidney damage and hearing impairment. For pregnant women and children, elderly patients and people with renal insufficiency, need to be used with caution, and those who are allergic to this type of drug need to be prohibited. Therefore, aminoglycoside antibiotics should be standardized under the guidance of a doctor, not recommended for self-medication.