At present, the commonly used clinical drugs for lowering urinary protein include angiotensin-converting enzyme inhibitors/angiotensin receptor II antagonists, glucocorticoids, immunosuppressants and monoclonal antibodies. 1. Angiotensin-converting enzyme inhibitor/angiotensin receptor II antagonist (ACEI/ARB): commonly used drugs include enalapril, valsartan, etc., which can effectively reduce urinary protein. 2. Glucocorticoids: commonly used are methylprednisolone, dexamethasone, etc. The hormones have strong anti-inflammatory and immunosuppressive effects, which can inhibit the immune inflammation of the kidneys, thus significantly reducing urinary protein. 3. Immunosuppressants: such as tacrolimus, morphemecogenol ester, cyclophosphamide, etc., the side effects of this type of drug is larger, often used in the treatment of large amounts of proteinuria patients, mild to moderate proteinuria is less used. 4. Monoclonal antibody drugs: such as rituximab, which is an anti-CD20 antibody, through the action of lymphocyte CD20 receptor, clear antibodies, reduce antibody deposition in the kidneys, so as to reduce renal damage, to achieve the effect of lowering urinary protein. When the urine protein is elevated, you should consult the nephrologist in time to find out the cause of the disease, and if necessary, renal puncture biopsy to clarify the cause of the disease, and under the guidance of the doctor’s medication, and regular review, do not use your own medication.