Professor Shi Zaixiang is the mentor of the third batch of national famous old Chinese medicine experts’ teacher-apprentice study. The author followed Shi’s consultation, and for many difficult cases in western medicine departments, such as intractable postoperative fever, the use of Chinese medicine can quickly reduce fever and relieve related symptoms. The unique advantages of traditional medicine were demonstrated, which convinced the western medical colleagues. The patient, Zhang Huiliang, female, 77 years old, case number 1113067, was admitted to our neurosurgery department on April 13, 2004 due to 4 years of vision loss, 2 years of nasal congestion, headache, and 1 year of right eyelid pain. Li Ge, Department of Integrative Cardiology, China-Japan Friendship Hospital Physical examination: clear consciousness, damage to the 1st, 2nd, 5th, 6th, 7th and 8th cranial nerves, visual field defects in both eyes, neurological deafness on the left side, damage to the abduction of the left eye, total blindness of vision, and decreased vision on the right side. Auxiliary examination: cranial CT and MRI showed: chordoma in the slope area. On April 22, he underwent chordotomy of the left maxillary reversal approach to the slope area under general anesthesia. On the 5th postoperative day, i.e., April 27, he developed fever, with body temperature above 38℃. Laboratory tests: sputum culture on May 8: methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-susceptible. pharyngeal swab culture on May 21: MRSA, nasal secretion culture on May 30: MRSA, routine blood count on May 8: WBC 4.58×109/L, N77.1%; L15.3%; HCT 26.8%; Hb94g/L. Western medicine treatment plan: several times change antibiotics, such as ceftriaxone sodium (Rochefort), fluconazole (Dafukang), etc. The effect is not good, in May 26th otorhinolaryngology consultation found a little pus cavity on the left nostril trauma, began to perform nasal flushing 3-4 times / day. On May 25, he started to use Vancomycin 0.5g Q8h and discontinued it on June 2. Body temperature did not subside. On June 2, he was consulted by Director Shi Zaixiang of the Department of Traditional Chinese Medicine (TCM). Summary of the four consultations: fever for more than one month, body temperature above 38℃, sweating, cold, dizziness, epigastric discomfort, yellowish moss and string pulse. Traditional Chinese medicine diagnosis: fever. I gave Dazhai Hu Tang with addition and subtraction. Initial prescription: Chai Hu 15g, Scutellaria baicalensis 15g, Citrus aurantium 12g, Radix Panax notoginseng 10g, Radix Paeonia lactiflora 12g, Radix jujube 10g, Radix ginger 10g, Radix rhubarb 6g, Radix chuanlian 6g, Radix guadua 15g. On the third day after the prescription, i.e., June 4, the body temperature dropped below 37℃ and the symptoms improved significantly. Since then, the body temperature has been maintained in the normal range. The second consultation was held on June 10 and the prescription was as follows: Chai Hu 10g, Huang Qi 10g, Cornu Cervi Pantotrichum 10g, Sheng Ma 10g, Zhi Mu 12g, Radix Platycodon 6g, Gypsum 30g, Huai Niu Knee 6g, Sheng Di 10g, Tian Mai Dong 10g each to consolidate the efficacy. Metronidazole (Methotrexate) 250ml, intravenous drip, Bid and Allicin 90mg, added to 5%; glucose injection, intravenous drip, Qd, were applied at the same time on June 2, until June 15, when the drug was discontinued and the disease was discharged. Discussion: In the late 1940s when penicillin was applied to treat staphylococcal infections soon after, drug-resistant Staphylococcus aureus and drug-resistant coagulase-negative staphylococci emerged. Currently, 90% of S. aureus are resistant to penicillin, and in 1960 the first penicillin-stabilized semi-synthetic penicillin called methicillin was developed for clinical use to overcome resistant bacteria. Unfortunately, methicillin resistant Staphylococcus aureus called MRSA (methicillin resistant Staphylococcusaureus) emerged in 1961, and since then it has gradually increased in prevalence in many countries around the world. early 80’s MRSA rose again in prevalence and increased dramatically in the United States, Canada, Australia, United Kingdom and European countries. MRSA is usually found on the skin, nose, ears, and external female genitalia, and generally does not require treatment for those who do not show symptoms. MRSA is found and spread mainly in hospitals and nursing homes, not through airborne transmission but through patient-to-patient and patient-to-patient contact. In particular, it is transmitted by hand contact and contact with skin insertion devices. MRSA infection is generally long, costly, difficult to eradicate, and life-threatening. Because MRSA is a multidrug-resistant microorganism, the choice of antibiotics for infected patients is extremely limited [2.3.4]. MRSA is resistant to penicillin antibiotics, first-, second-, and third-generation cephalosporins, and macrolide antibiotics, as seen in in vitro drug sensitivity tests. The resistance rate to aminoglycosides, quinolones, and tylenol exceeded 70%;. The only sensitive antibiotics are vancomycin and rifampicin [1, 5]. Patients with MRSA infections have the following characteristics: ⒈ older age; ⒉ most of them have underlying diseases such as diabetes, granulocyte deficiency, lung cancer, etc.; ⑶ some cases are treated with mechanical ventilation; ⒋ most of them have a history of using broad-spectrum antimicrobial drugs; and ⒌ the proportion of nosocomial infections is large and the disease is severe. Therefore, the possibility of MRSA infection should be considered in these patients (especially in nosocomial infections), especially when treatment with broad-spectrum anti-Gram-negative antibiotics is ineffective, and vancomycin should be used [6]. Vancomycin-resistant strains of MRSA have also been identified in recent years [7.8]. The patient in this case was 35 days postoperative with fever, chills, dizziness, sweating, and a stringent pulse. Bacteriological tests confirmed the diagnosis of MRSA infection. Conventional antimicrobial agents were ineffective. Vancomycin was given for 8 days with no significant effect. It was presumed to be a vancomycin-resistant strain of MRSA. After changing to the Chinese medicine Da Chai Hu Tang and using methotrexate and allicin (to prevent combined anaerobic and mycobacterial infections), the body temperature normalized and the symptoms improved. Da Chai Hu Tang is a formula for treating Shao Yang pivotal disorder and Yang Ming internal heat, which has the effect of relieving heat, draining the real, removing irritation and stopping vomiting. In clinical practice, this formula can be effective in treating Shaoyang disease with heat entering the lining or heat knotting in the stomach and intestines with addition and reduction. The main herbs of Da Chai Hu Tang are Chai Hu and Da Huang. Chai Hu is pungent and cold, and enters the Shao Yang meridian to release qi, elevate Yang Qi, and disperse evil; Da Huang is bitter and cold and enters the Yang Ming meridian to vent heat from the internal organs, invigorate blood and detoxify the body, and expel evil. The two are one on the table and one on the inside, one on the top and one on the bottom, combining the disease of Shao Yang Yang Ming and treating it, which is exactly what it is. Therefore, disharmony between the exterior and interior and disorder of elevation are the main indications for the use of Da Chai Hu Tang. In combination with discomfort in the upper abdomen and yellowish moss and other signs of damp-heat obstruction, the combination of Xiao Shen Che Tang is added to clear heat and dampness to broaden the chest. As she was an elderly woman with postoperative fever for one month, deficiency of both qi and yin was inevitable, so she was given the combined formula of Shengchi Tang and Yu Niu Decoction to improve the situation. This case is a world-wide problem faced by modern medicine in the era of antibiotics – the infection of broad-spectrum drug-resistant bacteria. Western medicine has no drugs available and is at its wits’ end. The traditional medical theory can make up for its shortcomings by using TCM evidence-based treatment, which is miraculous in its simplicity and brings out the charm of TCM.