High blood pressure and slow heart rate may be caused by normal negative feedback mechanisms, brain herniation and high blood pressure with hypothyroidism. It can be treated with medication, surgery and thyroid hormone supplementation as prescribed by the doctor. 1. Normal negative feedback mechanism: when the pressure receptors at the carotid sinus feel the change of elevated blood pressure, the activation of the pressure receptors results in the increase of vagal excitability, the decrease of sympathetic excitability and the slowing down of heart rate. At this time, high blood pressure can choose nifedipine controlled-release tablets, indapamide tablets and other drugs for antihypertensive treatment, avoiding the choice of metoprolol tartrate tablets and other beta-blocker drugs. 2. Brain hernia: As the patient’s brain stem is pressurized, it will cause symptoms such as elevated blood pressure, severe headache and slow and strong pulse. Furosemide tablets, mannitol injection and other drugs can be taken to reduce cranial pressure by dehydration treatment, but for patients who have already formed a brain hernia need to use surgical treatment, such as internal decompression surgery, decompression of the bone flap. 3. Hypothyroidism: high blood pressure with hypothyroidism, due to the reduction of thyroid hormone in the patient’s body, there will be a slow heart rate phenomenon. The patient’s heart rate will slow down due to the decrease of thyroid hormone in the patient’s body. The patient can follow the doctor’s prescription to supplement thyroid hormone drugs, such as levothyroxine sodium tablets, iodoselenin tablets, etc. When the patient has high blood pressure and slow heart rate, it is recommended to go to the cardiovascular department of the hospital in time for examination and treatment. Taking medication should be under the guidance of a doctor, not self-medication.