Chinese medicine considers night sweats in the second half of the night as night sweats, which are caused by Yin deficiency and Yang hyperactivity, i.e. Yin deficiency generates internal heat. From the modern medical point of view, sweating in the second half of the night occurs in more diseases, as follows: a. Infectious diseases: such as tuberculosis, prone to night sweating. Second, endocrine diseases: 1, hyperthyroidism: due to the high basal metabolic rate in the body, sweating increases, and can also sweat at night; 2, diabetes: usually the body is thinning leading to physical weakness, causing night sweats in the second half of the night; 3, menopause: women’s body estrogen and progesterone levels fluctuate, causing sweat gland secretion dysfunction, resulting in night sweats in the second half of the night. Third, rheumatic immune diseases: such as systemic lupus erythematosus, rheumatoid arthritis, etc., can lead to sweating in the second half of the night. Fourth, tumor diseases: such as hematological system tumors, including leukemia or lymphoma, etc., the patient’s physique depletion, can appear the symptoms of sweating in the second half of the night.