For the treatment of moles, surgical excision and laser “spot” moles are commonly used. The choice of treatment method generally takes into consideration the following factors: 1. size: generally, moles with diameter <5mm can be treated by laser and the scars are not obvious, otherwise they can be removed by surgery; 2. depth: some moles that do not protrude are often deeper, so if laser treatment is used, it is easy to leave a deeper pit, so surgical removal can be considered. On the contrary, some moles protruding from the skin surface can be treated with laser; 3. Location: Moles on the palms of hands, soles of feet, under finger (toe) nails, lips and external genitalia have the possibility of malignant transformation, so they can be removed prophylactically; 4. A mole that has been "spotted" cannot be used for pathological examination. If the benign or malignant nature of the mole is not clear, it is also recommended to take surgery and send the cut mole for pathological examination after the surgery.