Weakness of the hands and feet and panic may be due to coronary atherosclerotic heart disease, myocarditis, hyperthyroidism and other problems. 1. Coronary atherosclerotic heart disease: generally refers to coronary artery atherosclerosis, so that the lumen of the blood vessel is narrowed or occluded, resulting in heart disease caused by myocardial ischemia, hypoxia or necrosis, manifested as chest pain, chest tightness, soft hands and feet, panic and other symptoms, you can use clopidogrel hydrogencarbamate tablets, Tegretol and other drugs for treatment. 2. Myocarditis: it is generally an inflammatory disease caused by viral infection, manifesting symptoms such as chest pain, fever, arthralgia, arrhythmia, dyspnea, weakness of hands and feet, and panic, etc. It can be treated with medicines such as Metoprolol and Carvedilol. 3. Hyperthyroidism: generally due to the thyroid gland synthesizes and releases too much thyroid hormone, resulting in increased excitability of the nervous, circulatory, digestive and other systems and hypermetabolism, manifested as fear of heat, excessive sweating, panic, weakness of the hands and feet, etc., can be treated with medicines such as Methimazole tablets and Carbimazole. 4. Hypoglycemia: normal people such as long time not eat or control the amount of diet for weight loss, in addition, there are diabetic patients taking too much glucose-lowering drugs may trigger the occurrence of hypoglycemia, the appearance of soft hands and feet, panic and other symptoms, it is recommended to lose weight through reasonable exercise, diabetic patients should be based on their own condition of the rational use of medication to lower blood sugar, do not add their own medication. The above drugs should be used under the guidance of a doctor. Soft hands and feet and panic need to go to the hospital as soon as possible to confirm the diagnosis, under the guidance of the doctor’s instructions for standardized treatment.