On October 4, 2007, a patient suffering from a rare intracranial multiple basilar aneurysm, posterior cerebral aneurysm and posterior communicating artery aneurysm was successfully treated by microsurgical clamping in our neurosurgery department. Dr. Li Zefu received the patient on October 1, 2007, when she was admitted to our neurosurgery department due to a sudden explosion-like headache with nausea and vomiting, which had failed to be treated locally. According to the patient’s symptoms, a 64-row CT cerebral angiography (i.e. CTA) was performed to confirm the diagnosis of multiple intracranial basilar aneurysms, posterior cerebral aneurysms, and posterior communicating artery aneurysms. With intracranial aneurysms, the surgical risk is high, especially for the three aneurysms. The basilar aneurysm is located deep in the vertebrobasilar artery, which is deep in the brain and has important functions, so conservative treatment is life-threatening at any time. Faced with the patient’s serious disease, the expert team headed by Prof. Jianmin Li and Dr. Zefu Li decided to perform intracranial aneurysm clamping through careful analysis and research, consultation and discussion of treatment plan. After perfecting the preoperative preparation, the whole operation took only 4 hours, and all three aneurysms were clamped in one operation, which was very successful and eliminated the patient’s pain. The patient was successfully cured within a short period of time, reflecting the superb medical technology of our neurosurgery department and marking the level of vertebrobasilar aneurysm surgery in our hospital has entered the advanced ranks in China.