Anti-inflammatory drugs generally refer to antibiotics. Some antibiotics do not have adverse effects on the fetus when used correctly, but some of them may have toxic effects on the fetus, causing slow intrauterine growth and possible malformation in severe cases. Penicillin and cephalosporin antibiotics, which have low toxic effects, are generally not teratogenic to the fetus and can be used to treat various infections during pregnancy. However, pregnant women should not use large amounts of drugs privately, but need to use them under the guidance of a doctor and review the fetal growth and development status regularly after use. Macrolides, such as erythromycin, also have less effect on the fetus, and can be chosen by pregnant women with penicillin and cephalosporin allergy, but try not to use azithromycin, which can be toxic to the fetus through the placenta and can damage the fetus if used improperly. Quinolones, aminoglycosides, tetracyclines, sulfonamides antibiotics, are drugs prohibited during pregnancy. These drugs can enter the fetus through the placenta and cause fetal developmental disorders and multi-system malformations, especially in early pregnancy, which can cause serious adverse effects on the nervous system and eye development, resulting in neonatal mental retardation and visual impairment. Drug-induced fetal malformations are difficult to cure, and even if they can be born, they cannot be fully restored to health and have a low survival rate. Pregnant women should seek medical attention as soon as fetal abnormalities are detected after inadvertent use of drugs.