Premature ejaculation in men does not usually affect fertility, but if ejaculation occurs before vaginal penetration, it can affect fertility. Patients with premature ejaculation need to actively cooperate with doctors to take medication, psychological and behavioral therapy, so as to improve the symptoms of the disease and improve the quality of life. Premature ejaculation is a male sexual dysfunction disease that is categorized into primary and secondary. Primary premature ejaculation refers to the fact that from the first time of sexual intercourse, the ejaculation often or always occurs within one minute or less before or after vaginal penetration. Secondary premature ejaculation is a significant shortening of the ejaculatory latency, usually less than 3 minutes. Therefore, if penetration of the vagina and ejaculation is accomplished during sexual intercourse, it usually does not affect fertility, whereas if ejaculation has already occurred before penetration of the vagina it can affect fertility. Once diagnosed with premature ejaculation, patients can take oral selective 5 hydroxytryptamine reuptake inhibitors, such as dapoxetine, under the guidance of a doctor. At the same time with the squeeze method, stop moving method, functional sex therapy and other psychological and behavioral therapies, comprehensive treatment of the disease, most patients have a better prognosis. The above treatments usually cannot affect fertility either. If you have premature ejaculation or fertility-related diseases, please go to a regular hospital for timely treatment.