The newborn should be given at least 100 IU (preferably 200 IU) of high potency hepatitis B immunoglobulin (HBIG) within 12 hours after delivery (preferably within 12 hours after 2 hours of birth), and hepatitis B vaccine (yeast recombinant hepatitis B vaccine 10 μg or Chinese hamster oocyte hepatitis B vaccine 20 μg within 24 hours at different sites; preferably It is recommended that the child’s dose of “Anzai” be given preferably), and the immunization of hepatitis B vaccine should be completed according to the planned immunization program. It is also possible to give 1 dose of HBIG to a newborn within 12 hours after birth, followed by a second dose of HBIG 1 month later, and one dose of hepatitis B vaccine at different sites at the same time, with the second and third doses of hepatitis B vaccine given at intervals of 1 month and 6 months, respectively. With such treatment, the possibility of mother-to-child transmission can be reduced to less than 1%! Yi Jianhua, Department of Infection, Wuhan Union Medical College Hospital
Breastfeeding is possible after standardized treatment according to the above procedures.
As for some people advocate the injection of HBIG for pregnant women in the later stages of pregnancy (7th, 8th and 9th month of pregnancy) is a personal claim without evidence-based medical evidence, this practice is like throwing a grain of sand in the sea or sprinkling a drop of water in the desert, it is definitely ineffective; moreover, HBIG binds with hepatitis B virus antigen in the body to form immune complexes, which may be deposited in the glomerular basement membrane and other sites. Severe cases can even lead to hepatitis B virus-associated nephritis. If this is the case, it will be more than worth the loss!