Perianal warts, also known as condyloma acuminatum, is a sexually transmitted disease caused by human papillomavirus infection, once found need to seek medical treatment. Acromegaly is a common sexually transmitted disease caused by unclean sexual behavior. It occurs in the mucous membrane of the external genitalia or the junction of mucous membrane and mucous membrane, and some acromegaly may be transferred to other parts of the body, for example, warts of the external genitalia due to self-scratching, inoculation, and transferring to the anus around the edge of the anus, so it is also known as the perianal warts. Warts are usually transmitted mainly because of high-risk sexual behavior and sexual contact with warts patients or human papilloma virus carriers, plus when they are accompanied by breaks or fissures. When acromegaly occurs, it is necessary to clarify the diagnosis and then actively treat, avoid delaying the condition, follow the doctor’s instructions and reasonable treatment.