A variety of end-stage renal diseases are indications for kidney transplantation, which is currently receiving more and more attention as the incidence of kidney disease increases. Kidney transplantation is expensive, usually costing hundreds of thousands of dollars. The current cost of kidney transplantation comes from the cost of organ acquisition, the cost of clinical treatment, and the cost of appropriate medications. Kidney transplantation has become increasingly widespread since its inception and is an effective treatment for irreversible chronic renal failure. The corresponding access to organs has become more formal and secure, so the corresponding costs have become more uniform. Currently, kidney transplantation has a special importance among allogeneic transplants because it is the first and most effective. The surgical methods and post-operative management have become more and more standardized. The kidney transplantation procedure has been basically finalized, and in general, the recipient’s diseased kidney does not need to be removed, and the cost and trauma of the operation are more reasonable than before. The postoperative period is mainly for the prevention and treatment of rejection reactions. Some of the corresponding costs are relatively fixed and uniform. If there are no serious complications, like primary transplanted kidney non-function, transplanted kidney uretero-ureteric fistula, vascular embolism, recurrence of renal disease in the original kidney of the transplanted kidney, the corresponding costs are still relatively fixed. Currently, the corresponding cost of overall kidney transplantation is about 300,000 RMB.