How long do targeted drugs need to be taken long term to be effective

There is no exact time for how long a targeted drug can be effective. Those who are more sensitive to targeted drugs can see the effect in 1 to 2 weeks; some patients can see the effect only after 1 to 2 months, so the specific time to take effect needs to be decided according to their own situation.
The characteristics of targeted drug therapy are mainly targeting the various aspects of cell proliferation and infiltration, accurately killing tumor cells, thus improving the therapeutic efficacy and having less impact on normal cells.
Targeted therapeutic drugs for specific therapeutic targets mainly include gefitinib and erlotinib for EGFR gene-sensitive mutations, and trastuzumab and patuximab for HER-2 gene gene amplification. Multikinase inhibitors targeting multiple therapeutic targets mainly include sorafenib, sunitinib and so on.
Before taking a targeted drug, you need to undergo a combined multi-gene test to ensure that you can clearly find the therapeutic target of the targeted drug. If a clear therapeutic target cannot be found, the efficacy of the targeted drug will be poor and the targeted drug is not suitable for use.