The main cause of tympanic membrane invagination is pharyngeal canal inaccessibility, but there are many reasons for pharyngeal canal inaccessibility, mostly in children due to adenoid hypertrophy and hypertrophic rhinitis; in adults due to nasal diseases, such as hypertrophic rhinitis, polypoid changes at the posterior end of the inferior turbinate, nasal septal deviation, nasopharyngeal occupations, such as nasopharyngeal carcinoma, nasopharyngeal fibrovascular tumor, etc.; in addition, in the late stage of catarrhal otitis media, the fluid is partially absorbed and proteins are deposited in the middle ear cavity. The middle ear cavity is partially absorbed, causing the tympanic membrane to adhere to the middle ear, resulting in the formation of tympanic membrane invagination. Regardless of the cause of pharyngeal tube inaccessibility, negative pressure in the middle ear will result in tympanic membrane invagination, loss of light cone, shortening or diffusion. Tinnitus, such as wind, machine-like roar, cicada, etc., and stuffy ears, such as a foreign body filling the external ear canal, numbness and discomfort in the affected half of the head, may occur. Hearing loss also occurs. Treatment of the disease begins with identifying the cause and then treating the symptoms. If there is an occupying lesion in the nasopharynx, surgery or radiotherapy is required; for children with adenoid hypertrophy, adenoidectomy is required; whether caused by nasal diseases in children or adults, nasal lesions must be treated, such as hypertrophic rhinitis, surgical treatment of the inferior turbinate, nasal cavity dilation is performed to prevent the posterior turbinate from compressing the pharyngeal orifice of the eustachian tube; if the deviation of the nasal septum is severe, surgical correction must be performed. Once dysphagia is found, the cause should be identified and treated as early as possible to avoid sequelae, such as hearing loss and tinnitus, which may be difficult to cure, so I hope the majority of patients will pay attention to this. The above may be incomplete or missing, and we hope that our colleagues will criticize and correct us.