It is perfectly acceptable to apply ibuprofen for analgesia in patients who have intolerable pain after wisdom tooth extraction. In general, patients with mild or no significant pain after our routine dental extractions do not need to apply analgesic medication at this time. However, for the extraction of wisdom teeth, especially the extraction of buried wisdom teeth, because the extraction process often involves gingival incision, flap, removal of alveolar bone and tooth division, which is relatively more traumatic and takes longer, postoperative swelling and pain is also a common phenomenon. For this postoperative physiological pain, ibuprofen is a good choice. Ibuprofen is the first-line analgesic for mild to moderate pain as the first-stage analgesic for pain, and it has good analgesic effect and the side effects are not very big, so it can be used for analgesia after wisdom tooth extraction. There are different dosage forms of ibuprofen, including ibuprofen suspension for children and ibuprofen extended-release capsules for adults, so that different dosage forms can be used for different patients’ individual conditions.