The treatment of bipolar disorder depends on the patient’s symptoms, severity of illness, past medication history, psychological characteristics, and environmental factors. Patients with severe disease, such as those with significant risk of self-injury, suicide and impaired social functioning, require hospitalization. Whether the patient is in a manic or depressive state, he or she should be treated with mood stabilizers or antipsychotic drugs. Commonly used mood stabilizers include lithium salts and sodium valproate, and commonly used antipsychotics include olanzapine, haloperidol, quetiapine and others. Laboratory tests, such as routine blood tests, liver function, kidney function, electrocardiogram, etc., should be completed before medication, and blood levels of medication should be checked for 1-2 weeks. If the patient’s depressive symptoms are very serious, antidepressants can also be added, and bupropion without transthyretic effect or fluoxetine and paroxetine with weaker transthyretic effect should be selected. The patient’s symptoms should be closely observed, and if it turns into a manic episode, antidepressants should be stopped immediately to avoid aggravating the manic symptoms. In addition, the treatment in the non-acute stage is also important, which is to carry out psychological treatment and intervention according to the psychological characteristics and environmental factors of the patient, eliminate the psychological and environmental factors unfavorable to the recovery of the disease, and enhance the self-confidence of the patient and the self-confidence of the treatment.