Drugs for the treatment of insulin resistance mainly include metformin and thiazolidinediones.
Among the biguanide drugs, metformin has a very good effect in improving insulin resistance. Metformin can not only increase the utilization of hepatic glycogen by peripheral tissues and muscles, but also significantly improve insulin resistance, increase the utilization of glycogen, and then improve the effect of insulin sensitivity.
Thiazolidinediones are insulin sensitizers, which can enhance glucose uptake by skeletal muscle and adipose tissue and reduce their resistance to insulin, reduce the breakdown of hepatic glycogen, and improve the secretory response of beta cells to insulin. Reduce insulin resistance, improve β-cell function and improve glucose metabolism. Commonly used drugs such as rosiglitazone and pioglitazone.
All of the above drugs have certain risks, and insulin resistance needs to go to the hospital for further diagnosis and treatment under the guidance of specialists.