Neonatal jaundice is divided into physiological jaundice and pathological jaundice, and the treatment of the two is different. Physiological jaundice is formed due to the physiological structure of the child and usually appears 2-3 days after birth, the value is not too high and usually subsides in about 14 days, during this period drink more water and pay attention to monitoring the child’s bilirubin value. 2, pathological jaundice generally appears early, or disappears slowly, and the bilirubin value is higher. The causes can be divided into excessive blood cell destruction, infectious factors and the liver itself, which require symptomatic treatment. If there is hemolytic jaundice, blue light and jaundice-reducing medication should be administered in a timely manner, which may lead to bilirubin encephalopathy if not treated properly. If the disease is caused by infectious factors, such as cytomegalovirus infection or rubella virus infection, antiviral drugs and liver-protective drugs should be given to treat the root cause. If the bilirubin level is high due to a genetic metabolic disorder, the patient should be treated with jaundice reduction medication, blue light, and identification of the cause and the digestive enzyme deficiency. If it is a problem with the liver itself, such as a blockage of the bile ducts, this can only be relieved by surgery. If the bilirubin value is too high, it should be treated promptly, otherwise the value exceeds 20mg/dl, it may lead to bilirubin encephalopathy, once the bilirubin encephalopathy is formed, it is easy to cause intellectual damage and behavioral damage to the child, which may lead to disability of the child and needs to be paid high attention.