The most advanced, ideal, least invasive, effective and efficient treatment equipment is the Swiss 5th generation EMS lithotripsy system. It is especially effective for large and hard stones. The chance of surgical complications is significantly reduced. Indications for percutaneous nephrolithotomy and ureteroscopy: 1. Complex kidney stones: multiple, cast stones. 2, Residual kidney stones: after open surgery, after ESWL. 3.Special kidney stones: isolated kidney, transplanted kidney, horseshoe kidney. 4.Symptomatic infrarenal calyces stones, diverticula stones. 5, UPJ obstruction combined with kidney stones. 6.Ureteral upper segment stone: large stone, embedded package, failed ureteroscopy. 7, Infected stones, ESWL and drug lithotripsy treatment is ineffective, ureteral stone street after ESWL treatment.