Cryotherapy is a method of applying low temperature to lesions to cause necrosis or induce biological effects in order to achieve therapeutic goals. Because of its simplicity and ease of use, it is widely used in dermatology. Refrigerant: At present, the clinical department of dermatology mainly uses liquid nitrogen, which has a low refrigeration temperature and a boiling point of -196°C, and has a large destructive effect on tissues. According to the size of the lesion, prepare the corresponding cotton swab and dip it in liquid nitrogen, then quickly place it on the lesion and apply a certain pressure. The rate of cure for common warts can be over 95%. For perineal warts, cryotherapy is preferred because it does not affect nail growth by damaging the nail matrix. The pain level of cryotherapy for perineal warts is quite high and mostly in children, so I would recommend local anesthesia so that children can be treated with cryotherapy without pain and with better results. In addition to other warts such as condyloma acuminata (especially vulvar condyloma of pregnant women), flat warts (facial generally not used), infectious molluscum contagiosum (especially for children’s infectious molluscum contagiosum, laser treatment requires local anesthesia, children are generally difficult to cooperate, while liquid nitrogen freezing does not require anesthesia, generally only one treatment can be cured), seborrheic keratosis (age spots), nodular itchy rash, skin amyloidosis, etc., freezing The treatment has good efficacy. In order to improve the efficacy of treatment generally requires multiple treatments, individuals recommend a one-month interval between scab off and then cryotherapy, before treatment should be as far as possible to remove the surface hyperplasia of keratin. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. 2, after freezing, in general, the first three days it is recommended to freeze local do not soak water, appropriate can contact water, in case the water (blood) blisters touch broken, do not touch the water, you can use topical anti-inflammatory ointment to prevent infection. The picture of the follow-up three weeks after treatment, you can see that part of the scab has fallen off. 3, the next time to do cryotherapy need to wait for the scab to fall off naturally, the hands and the back of the foot generally interval of about 3 weeks, the soles of the foot generally interval of about 4 weeks. After the scabs fall off, the base is smooth and flat that is cured. The back of the hand, back of the foot warts generally do 1-2 times liquid nitrogen freezing treatment can be cured, the palm of the hand, plantar warts need 2-4 times, or even more liquid nitrogen freezing treatment to cure.