Calcitonin is a peptide hormone, which can rapidly inhibit osteoclast activity and slowly act to reduce the number of osteoclasts, with the function of pain relief, increasing the function of activity and improving calcium balance, and has a pain-relieving effect on patients with fractures, and is suitable for patients with contraindications or intolerance to diphosphonates and estrogen. Commonly used domestic preparations include calcitonin (Miacalcin, salmon calcitonin) and etacalcitonin (Icariin). Calcitonin is administered parenterally and intranasally in 2 ways, and the duration of action of parenteral administration can last for up to 20 months.