It has also been demonstrated that the levator muscle has fewer synaptic folds and fewer AChR and Na+ channels, which tend to reduce the safety margin and exacerbate muscle junction transmission impairment in pathological situations. In addition, the immunopathological process of myasthenia gravis involves complement, and the expression of complement regulatory proteins is less in the levator muscle than in other skeletal muscles. Complement regulatory proteins can inhibit complement function, and if complement regulatory proteins are less expressed, it means that complement activation is not easily terminated once initiated, so it can be hypothesized that the levator muscle is more susceptible to complement-mediated pathological processes.