It is possible to develop spider nevi with a small triple diagnosis. Spider nevi (also known as spider capillary dilatation) are vascular lesions consisting of a small central artery and many smaller blood vessels around it. They are most commonly found on the trunk, face and upper extremities. When the lesion (small central artery) is pressed with a slide, it is seen to pulsate. After a brief period of ischemia that causes the skin to suddenly turn white, blood first fills the small central artery and then flows to the tips of the tiny peripheral branches of each “leg”. There are usually multiple radiating “leg” branches and peripheral erythema, which may encircle the entire lesion area or only the small central artery. The pathogenesis of spider nevi is not fully understood, but it is currently believed that they result from altered sex hormone metabolism. Spider nevi may develop as a result of the development of cirrhosis. However, acquired spider nevi are not unique to cirrhosis, as they are also seen in pregnant women and in patients with severe malnutrition. Acquired spider nevi, usually less than 3 small lesions, can also occur in otherwise healthy people. In general, the number and size of spider nevi correlate with the severity of liver disease. Patients with many large spider nevi may be at increased risk for variceal bleeding. In summary, patients with hepatitis B teratitis minor are advised to actively follow their doctor’s instructions to slow down the progression of their disease.