Hazards easily generated in the process of infusion: 1. Fever reaction Input of thermogenic substances, imperfect cleaning and sterilization of infusion bottles or contamination can lead to chills, chills and fever in patients, and high fever of 40 to 41 degrees Celsius in serious cases. 2. Pulmonary edema Because the infusion speed is too fast, too much liquid is input in a short period of time, the circulating blood volume increases dramatically and the heart is overburdened, causing edema, which is life-threatening in serious cases. In patients with a history of heart failure or heart disease, rapid and massive infusion may aggravate heart failure, and in severe cases, may induce pulmonary edema. 3, phlebitis Because the long-term infusion of too high concentration and strong irritation of the drug solution, or irritating plastic tube placed in the vein for too long, can cause the chemical inflammatory reaction of the local vein wall, but also because the aseptic operation in the infusion process is not strict, causing local venous infection. 4.Air embolism The reason is that the air is not exhausted during the infusion, and the rubber tube is not connected tightly with leakage slit. As long as a small amount of air enters the vein, the patient will feel abnormal chest discomfort, followed by respiratory distress, severe cyanosis and lack of oxygen, and can lead to sudden death. 5, “malignant” adverse drug reactions playing drip than oral drugs are also more likely to have adverse drug reactions, especially allergic reactions. If it is taken orally, the impurities in the drug that can cause allergies may be digested in the digestive tract, or can not be absorbed by the body, but these impurities enter the bloodstream directly when playing an IV, which can cause anaphylaxis or even death in severe cases. Recently, there have been frequent media reports of patients suddenly dying from the use of Chinese medicine injection, which is caused by this reason, and there was also a media report of a hospital finding black flocculent in the infusion bottle. Some doctors said “adverse drug reactions are ultimately the cause of the drug itself, but the intravenous drip has led to the exacerbation of such adverse reactions, which can seriously lead to shock or even death. “Xinfu” injection, fishy grass injection, acanthopanax injection, Yinjianhuang injection caused serious adverse reactions to people shocking, lingering pain. 6, granuloma hazard Recently, a 25-day newborn in the United Kingdom died of enteritis, the late treatment had thousands of milliliters of infusion, found granuloma in its lung pathology section, which is caused by a large number of insoluble particles brought by infusion. In recent decades, the hazards of insoluble particles during infusion have been gradually recognized. The human naked eye can see particles with a diameter of 50 microns or more, and it is precisely those harmful particles with a diameter between 2 and 50 microns that are invisible to the naked eye, move and cannot be metabolized in the body that enter the blood vessels, leading to various infusion contamination diseases. The large number of particles that enter the body with the infusion are engulfed by macrophages, which can enlarge the macrophages and form granulomas. One scholar conducted an autopsy on a cadaver that had been infused with 40 liters of “hanging bottles” in its lifetime and found that the cadaver had more than 500 granulomas and a large number of microvascular blockages in the lungs alone. 7, medical source of infection In several ways of drug delivery, the drip is the most dangerous. The drip penetrates the skin barrier and feeds the drug directly into the bloodstream, requiring strict aseptic processing. If the drug solution is contaminated during production or storage, or if disposable needles are not used, or if the skin at the site of needling is not properly sterilized, it may allow viruses and germs to enter the body, causing local inflammation in mild cases, or in severe cases, the pathogen may spread throughout the body with the blood and cause sepsis, which can be life-threatening. If the medical environment is not completely sterile, it can lead to cross-infection.