The warts can be removed through medication, physical therapy, and surgery, along with the use of antiviral drugs to inhibit the growth of the virus and prevent recurrence. 1. physical therapy: including laser, freezing, electrocautery treatment, etc., for small warts, not a lot of warts, usually through physical therapy can be removed all the warts. 2. Surgery: If the perianal warts are large and numerous, it is recommended to use surgery to remove them, and the removed warts can be sent to the pathology laboratory to further clarify the diagnosis. 3. Drugs: After removing the warts through the above methods, you can use interferon gel topically. As the anus is often in a moist state, is not conducive to the recovery of postoperative wounds, in the post-surgery need to pay attention to the perianal skin clean and dry. As the acromegaly has a certain chance of recurrence, you need to follow the doctor’s instructions for regular review after the operation.