Trigeminal neuralgia can be tolerated? The first reaction of many patients with trigeminal neuralgia is to endure it anyway. Trigeminal neuralgia is a disease that does not heal itself, and the condition will only get worse with delay. The pain of trigeminal neuralgia will make the central nervous system in a state of excitement, sympathetic excitability increases, which can be manifested as increased secretion of catecholamines and enhanced glycogenolysis, many trigeminal neuralgia patients dare not eat, and the body is in a negative nitrogen balance. 2, mental changes Trigeminal neuralgia has a great impact on the mental and psychological state, relatively speaking, it is a recurrent paroxysmal severe pain, patients are often afraid to eat, wash their faces, rinse their mouths and brush their teeth, which leads to malnutrition and stained face of patients. This has a tremendous impact on the patient’s mental and psychological state. Patients will be anxious, irritable and irritable, and some of them will be pessimistic and disappointed, depressed, intolerant of pain, and in a state of inhibition of mental activity, and may even have thoughts of lightness of life. Long-term depression will make the patient’s response to external changes dull. 3, physiological impact The impact of trigeminal neuralgia on physiological movement is self-evident and very significant. Whether the pain is acute or prolonged, it will cause a series of changes in physiological activities such as digestive system, starting organism nerves, circulatory system, respiratory system secretion. The constant painful stimulation of trigeminal neuralgia causes changes in a series of physiological activities such as secretion of the central nervous system. Microvascular decompression is the only method to treat the cause of trigeminal neuralgia, which can directly reach the responsible vessels to release the vascular and nerve compression, shorten the operation time, and reduce the incidence of surgical complications. The procedure is able to preserve the anatomical integrity of the trigeminal nerve, so the function of the trigeminal nerve can be preserved. Because microvascular decompression has the advantages of obvious pain relief, non-destructive, less side injuries, and very low recurrence rate, it has become the safest and most effective method for the treatment of trigeminal neuralgia that is internationally recognized.