For patients with declining ovarian function, it is important to choose the right treatment. This requires going for the right modality depending on the individual’s situation. Younger women may consider hormone replacement therapy. Younger women with declining ovarian function will also have less estrogen in their bodies. In the long run, they will have a series of problems such as painful intercourse, shrinking of the uterus, reduced vaginal discharge, and in some cases, osteoporosis. Women with fertility needs can take ovulation medication at the same time. With the recovery of the ovaries, most women can achieve their desire to have children. Patients who have been tested and confirmed to have antibodies in their bodies can opt for immunotherapy. With the development of medical technology, the effectiveness of immunization vaccination has become more and more obvious and reliable. Patients with nutritional deficiencies of the ovaries and those with advanced stages of ovarian decline need to consider surgical treatment. Surgery for ovarian transplantation is performed as soon as possible before complete loss of ovarian function. Patients with declining ovarian function must first identify the cause of their disease and understand their physical condition before choosing a targeted treatment. Not only will haphazard treatment fail to achieve results, but it may harm the body.