Recently, many people have come to the hospital to ask for mole removal after watching Li Xiangshan in the famous director Feng Xiaogang’s “Do Not Disturb 2” died because of the transformation of mole into malignant melanoma, I would like to tell you here that laser mole removal is a pulsed CO2 laser, which can act on the water in the tissue and produce vaporization or charring effect on the mole tissue. By precisely vaporizing or charring the mole tissue, the mole tissue can disappear completely, while the damage to the normal skin next to it is very small and can heal by itself, usually leaving no obvious scars. However, we should pay attention to the following matters: 1. Be sure to go to the dermatology department of a regular hospital and ask a doctor who has been engaged in skin laser operation for a long time to decide whether to remove the mole by laser or by surgery; 2. After laser removal, you should apply antibiotic ointment (gentamycin hydrochloride, erythromycin, Bactrim, etc., for 5-7 days) to ensure that the wound surface is moist and clean and avoid getting wet; 3. Do not scratch, and do not peel off the scab (let it fall off naturally), avoid exposure to the sun to prevent pigmentation; 4, if there is a recurrence, usually more than 2 to 3 months before the next treatment, the next recurrence, laser treatment is not recommended, feasible surgical removal or no treatment.