Smoker’s disease is a relatively rare cerebrovascular disease that was first identified and named by Japanese medical experts in the 1950s and 1960s. The disease is caused by chronic progressive narrowing or occlusion of the major arteries in the brain, which leads to compensatory proliferation of the vascular network at the base of the skull, forming a network of small, fragile vessels that appear as a cloud of small smoke-like vessels during imaging, hence the Japanese image of smog. Some people who are diagnosed with smog ask if it can be cured because they do not understand the disease and have never even heard of it. In fact, patients do not need to worry too much, as smog can be cured. For a period of time, medical treatment for smog was not very good. But in recent years, with the continuous development of medical technology, this disease can be treated very well. Smog is mainly caused by the obstruction of blood flow in the skull, so the brain can be cured by cerebrovascular bypass surgery to re-establish good blood flow to the brain and restore normal blood supply to the brain. There are direct vascular bypass, indirect vascular bypass and combined vascular bypass, compared to combined vascular bypass surgery, which can achieve more ideal treatment results. Combined vascular bypass surgery is a combination of direct bypass + patching, both of which are done in the same surgery. The direct bypass can rapidly improve the cerebral blood supply, while the multi-factor patching can induce neovascularization in a larger area and expand the scope of vascular improvement. Therefore, smog disease is clinically curable, and combined vascular bypass surgery can accomplish good blood flow reconstitution and improve cerebral blood supply comprehensively with a two-pronged approach to achieve better treatment results.