Coagulation factor 12 deficiency is a deficiency of the coagulation factor E.D., which is a possible cause of thrombophilia, as well as other disorders such as congenital E.D. deficiency, liver disease, disseminated intravascular coagulation, and certain other thrombophilic disorders.
The main causes of thrombophilia are congenital factors such as deficiency of anticoagulant protein C, deficiency of coagulation factor D.E., and genetic mutations that result in abnormal function of the anticoagulant system, as well as acquired factors such as infections, tumors, and pregnancy.
Coagulation factor E3 deficiency may also be due to congenital E3 deficiency, liver disease, disseminated intravascular coagulation, and certain other thrombotic disorders.
The presence of coagulation factor D deficiency should be promptly consulted and treated under the guidance of a doctor, and daily attention should be paid to a healthy diet, rest, self-protection, and avoidance of strenuous exercise.