The cost of atrial septal defect blocking is about $20,000, but the type of blocking surgery and the materials used will vary for different degrees of atrial septal defect, and the complexity of the surgery will also vary, so the price will also vary. If the surgery is more complicated, it may cost about 50,000 yuan. In addition, before the surgery, the patient’s general condition needs to be evaluated by completing relevant laboratory tests and examinations to see if the patient is suitable for the surgery. Antibiotic medication should be given to prevent infection, which will cost about 5,000 yuan. After the surgery, cardiac monitoring, cardiac muscle nutrition, circulation improvement and other symptomatic treatment are needed, which costs about 5,000 yuan. If the complications of surgery are many and serious, long-term admission to the intensive care unit may be required, which requires a case-by-case analysis.