At present, there are two main categories of injectable cosmetic items: botulinum toxin and injectable fillers, the former is mainly used to relax tense muscles, thereby obtaining the cosmetic effect of wrinkle removal or face slimming, the latter is mainly used for facial rejuvenation and shaping, including wrinkle removal, improvement of skin pigmentation, improvement of skin quality, etc. At present, domestic dermal fillers can be divided into two categories: one is permanent or semi-permanent fillers such as: Iverland, At present, domestic dermal fillers can be divided into two categories: one is permanent or semi-permanent fillers such as: Iverland and Avef, and the other is non-permanent fillers such as: collagen (Shuangmei 1), hyaluronic acid (Ruilan and Yimei), etc. Permanent fillers contain materials that are not absorbed by the body at all or some of their components are not absorbed, so a one-time injection can maintain long-lasting effects. Non-permanent fillers, which can be completely degraded and absorbed by the body, have a relatively short duration of action. The current non-permanent fillers generally last 6-12 months in the human body and require regular supplemental injections to maintain long-lasting effects. In terms of cosmetic effect, permanent fillers cannot change adaptively with the change of facial contour, and when the facial contour changes with age, permanent fillers will become a new defect. Non-permanent fillers, which are fully compatible with human tissues, can stimulate the production of collagen by autologous cells and facilitate the doctor to adjust the injection according to the changes of facial contour at any time, so that the facial contour can be maintained in a youthful state for a long time. It is worth noting that many permanent or semi-permanent fillers have had their licenses cancelled or not renewed by the State Drug Administration due to many serious complications. Those currently approved for clinical use are non-permanent dermal fillers, which are completely degradable in the human body. It is important to know the name, origin, and specifications of the injectable drugs that have been approved by the state before the injection, and to see if they are consistent with the homework you have done at the place of injection, to ensure that the drug injected for you is a state-approved product.