The starting dose of sertraline for the treatment of premature ejaculation is 25mg once daily in the morning or at night, with slow dosage increases, and should be used as prescribed by your doctor. Sertraline is a selective 5-hydroxytryptamine reuptake inhibitor, used for the treatment of premature ejaculation, the starting dose of 25mg once a day, morning or evening, after a week, the dose can be increased to 50mg per day, and thereafter the dose should not be adjusted at intervals of less than 1 week, the maximum dose of 200mg per day. the above usage as a reference, the specific should be in accordance with the doctor’s instructions. Sertraline is contraindicated in individuals who are hypersensitive to this drug and should not be combined with monoamine oxidase inhibitors such as selegiline or pimozide. Adverse reactions such as dry mouth, excessive sweating, dizziness, tremor, diarrhea, and indigestion may occur after use. Sertraline for premature ejaculation should be used under medical supervision.