Male infertility is defined as male infertility when the couple has lived together for more than 1 year, has regular sexual intercourse without contraception, the female partner is infertile, and the male partner has an abnormal examination. According to the history of pregnancy of the female partner, it can be divided into primary infertility and secondary infertility. The common disorders of male infertility are: azoospermia, oligospermia, hypospermia, and semen indigestion, etc. Several conditions may exist in colleagues. The basic tests related to male fertility are: physical examination, semen analysis, and endocrine hormones. If the examination suggests azoospermia, or severe oligospermia, further examinations such as chromosome, Y chromosome microdeletion, semen exfoliation cytology, epididymal testicular puncture, etc. will be performed according to the situation. If the examination suggests oligospermia or weak spermatozoa, a combination of Chinese and Western medicine will be used depending on the situation. Regarding the liquefaction of semen. In the case of normal sperm vitality, no special treatment can be given for semen non-liquefaction; in the case of poor sperm vitality, semen non-liquefaction can be treated at the same time. Infertility advocates that both men and women should be examined or treated. If both men and women have no abnormalities, and if it is difficult to get pregnant for a long time, artificial insemination or in vitro fertilization can be considered. We suggest to go to a specialist hospital for examination and effective birth control as soon as possible after pregnancy, because of the current environment and food pollution, etc.