Patient Question: Dr. Lee, why do I have blepharospasm? What can I do to make this disease better? Dr. Lee: The etiology and pathophysiology of benign idiopathic blepharospasm (BEB) is unclear. Most scholars believe that the pathogenesis of BEB may be related to damage to the basal ganglia of the brain, resulting in dopaminergic receptor hypersensitivity or dopamine transmitter imbalance and overactivity of cholinergic nerves. Blepharospasm is related to mental stress and fatigue. When a person is mentally stressed or physically fatigued, when the eyes are overused or when the eyes are irritated by sunlight or sand, the symptoms can worsen the attack. Also, it is associated with a number of eye diseases. For example, it is usually combined with diseases such as dry eye, upper eyelid skin loosening, and ptosis. In addition, other eye diseases such as blepharitis and conjunctivitis can increase transients, which can gradually worsen the blepharospasm. You should try to rest and relax emotionally after the disease, and if there is no improvement, you must seek medical attention in a timely manner so that the condition does not worsen and make treatment more difficult.