Children spitting white foam at the mouth while sleeping is mostly considered to be caused by normal phenomenon, oral diseases, pediatric pneumonia, pediatric epilepsy, etc. They need to go to the hospital for examination and treatment after clarifying the causes. Common causes and treatment a. Normal factors: children’s salivary gland development and function gradually improved, the amount of saliva secretion gradually increased, the oral action will also increase, appearing to stretch out the tongue and spit white foam. It is a normal phenomenon, and will gradually disappear with age and the perfection of swallowing function; Second, disease factors: 1, oral diseases: such as herpes stomatitis, thrush, etc.. Inflammation and ulcers can cause stimulation of the oral mucosa, promote salivary gland secretion, resulting in children sleeping with white foam at the mouth situation. Herpetic stomatitis can be treated locally with acyclovir ointment to inhibit the virus, while paying attention to oral hygiene. The child with thrush can use 2% sodium bicarbonate solution to clean the mouth before and after breastfeeding; 2. Pediatric pneumonia: frothing at the mouth while sleeping is one of the manifestations of pediatric pneumonia, which can also be accompanied by fever, refusal to eat, choking, vomiting, depression and other symptoms. The patient’s blood tests, pathology and chest x-ray should be completed. If the blood tests indicate bacterial infection, the patient should be treated with antibiotics, such as mycoplasma pneumonia, macrolides, erythromycin and roxithromycin, and viral pneumonia, interferon and other drugs. The child should immediately go to the hospital, improve the EEG, cranial CT examination, treatment can be prescribed to be phenobarbital, carbamazepine, sodium valproate and other drugs. Parents should also pay close attention to the child’s mental state.