Acanthosis vulgaris is an idiopathic benign disease of the cutaneous appendages, mainly on the face, especially around the eyelids, cheeks and forehead. Typical lesions are 1 to 2 mm in diameter, multiple, nonconfluent, and may extrude white keratinous granular material. The disease is divided into primary and secondary lesions. Primary lesions appear after birth or in early childhood and have an unclear etiology; some patients have a genetic component to their onset, which may subside spontaneously. Secondary damage often occurs after other skin diseases, most commonly after abrasions, dermal porphyrias, herpetic epidermolysis bullosa, herpetic dermatosis, second-degree burns, and herpes zoster, etc. Secondary damage mostly occurs around pre-existing skin diseases. The disease is mainly treated topically, or may not need to be treated. If it is needed for cosmetic reasons, it can be treated in a standardized manner under the guidance of a physician to avoid causing secondary damage such as infection. For individual rashes, with attention to asepsis, the skin on the surface of the cornea is first disinfected with 75% alcohol and then punctured with a fine needle to squeeze out the white contents, avoid water, and leave to dry and crust. When there is more damage, it is not recommended to treat it by yourself and you need to consult a doctor. Others such as using appropriate cosmetics to cover up or topical medications are also a good way to go. The treatment of milia is mainly localized, but since the lesions mainly occur in the facial area, improper treatment will not only fail to achieve cosmetic results, but will even affect the aesthetics, so when there are more lesions, you should consult your doctor for reasonable treatment.