Hiccups are a common phenomenon in daily life, and there are many medicines for treating hiccups, which should be taken as symptomatic treatment for different etiologies. For slowed gastrointestinal motility and insufficient gastric motility caused by digestive disorders, pro-gastric motility drugs, such as domperidone, cisapride and mosapride, can be given. For hiccups caused by indigestion, stomachic and antiphlogistic drugs should be given, such as stomachic and antiphlogistic tablets, yeast tablets, hawthorn pills, etc. For hiccups caused by certain organic diseases, such as gastric ulcer, duodenal bulb ulcer, bile reflux gastritis, etc., where the patient also has symptoms such as acid reflux, belching and heartburn, proton pump inhibitors, such as omeprazole, pantoprazole and rabeprazole, should be given. If the symptoms of hiccups occur repeatedly, one should go to the hospital for relevant auxiliary examinations, such as gastroscopy, to clarify the cause of hiccups and give active treatment.