The difference between drug balloon and stent includes different materials, different indications and different effects after treatment. 1. Different materials, drug balloon is flexible, and there are some anti-vascular endothelial cell proliferation drugs on the surface of the balloon, while the stent is usually made of metal material, and there are drug stent and bare stent. 2. Different indications, drug balloon is mainly applied to some small vessel stenosis or stenosis formed again by placing stent. The indications of stent are wider, especially when moderate or severe stenosis affects local function, stenting can be considered. 3. Different effects after treatment, drug balloon has the effect of expanding blood vessels, inhibiting the growth of vascular endothelial cells, and does not stay in the blood vessels after treatment, but the probability of future restenosis is higher; stent treatment is permanently placed in the blood vessels, especially drug stents are coated with medication, which is capable of preventing the restenosis of blood vessels. In short, there is a difference between drug balloon and stent, and it is recommended that patients go to the cardiology department of the hospital, and the doctor will make a comprehensive analysis according to the patient’s condition, age and other circumstances to determine the best treatment plan.