In general, the injection of either the new crown vaccine or other vaccines does not affect the results of the nucleic acid test and can be performed at any time. However, if an inactivated vaccine is administered, it is best to perform the nucleic acid test the next day. This is because an inactivated vaccine is a vaccine made from a pathogen, such as the New Coronavirus, that has been inactivated and contains the nucleic acid sequence of the pathogen. During vaccination, during operations such as extraction and syringe venting of the vaccine, the vaccine may float in the air as a liquid or aerosol, directly or indirectly contaminating the vaccination site, vaccination personnel, and the vaccine recipient, etc., resulting in the presence of pathogen nucleic acid fragments in the nasal or pharyngeal mucosa of the vaccine recipient, and false-positive results may occur when testing nucleic acid in nasopharyngeal secretions. When tested the next day, the nucleic acid fragments of the new coronavirus can be excreted with the nasopharyngeal secretion, and the residual nucleic acid fragments will be greatly reduced, which can reduce the false positive rate. If the nucleic acid test is positive after vaccination, you need to explain the vaccination to your doctor and retest 2 days later to clarify the presence of pathogenic infection. If the vaccination is a recombinant vaccine or an adenovirus vector vaccine that does not contain the nucleic acid sequence of the virus and does not contaminate the environment or the recipient, the timing of viral nucleic acid testing is not limited by the vaccination of the new crown vaccine and testing can be performed at any time.