In general, only neonatal jaundice can subside spontaneously in 7-10 days, while pathological jaundice due to other causes cannot subside without effective treatment. It can also be life-threatening if not treated early and aggressively, such as pathological jaundice in infants, hemolytic jaundice due to liver injury, and extrahepatic obstructive jaundice due to malignant tumors. Pathological jaundice in infants can cause neurological damage and is easily complicated by bilirubin encephalopathy and severe bilirubin encephalopathy, which has a high mortality rate. Liver injury without aggressive treatment can lead to hepatic necrosis, resulting in human death. Obstructive jaundice due to cholangiocarcinoma can also be life-threatening if not treated aggressively.