Quick treatment options for cracked corners of the mouth include stopping medication, topical immunomodulators, and oral or topical antiviral medications to target the cause. If the cracked mouth is caused by the use of certain medications, stopping the medication under the supervision of a doctor and applying lip balm to the corners of the mouth can effectively heal the cracked skin. If the cracked lips are caused by exfoliative lipitis, topical immunomodulators such as tacrolimus ointment and pimecrolimus ointment can be used, and the symptoms of cracked lips will gradually improve. If the cracked corners of the mouth are caused by herpes simplex virus infection, the symptoms can be improved quickly by taking oral valacyclovir hydrochloride and using topical acyclovir cream. If you find cracked corners of the mouth, you should consult a doctor without authorization, so as not to delay the condition. Pay attention to oral hygiene care, eat less spicy food, quit smoking and drinking, and maintain a regular routine.