(Disclaimer: This article is for scientific purposes only. To protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: 75-year-old Uncle Chen reported that he had recently developed fever 3 months ago, accompanied by night sweats. He was treated with anti-inflammatory therapy with cefdinir capsules in the emergency department, and the fever symptoms subsided. Recently, however, the fever symptoms appeared again, and the oral antipyretic drugs did not show significant improvement. The patient was diagnosed with cellular lymphoma after relevant examinations, and the condition was well controlled after chemotherapy, and the fever disappeared. Basic information] Male, 75 years old [Disease type] Acellular lymphoma [Hospital] The First Affiliated Hospital of Xi’an Jiaotong University [Date of consultation] January 2021 [Treatment plan] Intravenous (cyclophosphamide for injection, epirubicin hydrochloride for injection, vincristine sulfate for injection) + oral drugs (prednisone acetate tablets, omeprazole enteric-coated capsule, ranitidine hydrochloride capsule) [Cycle of treatment Hospitalization for 16 days, return to the hospital after 2 weeks for the next cycle of treatment 【Treatment effect】 Fever symptoms disappeared and the condition stabilized I. Initial interview The patient reported that she had fever without any trigger 3 months ago, accompanied by night sweats, but no cough, nasal congestion and other discomforts. Recently, her appetite was poor, but she gradually gained weight locally. Relevant examinations were prescribed after obtaining the patient’s consent, and the results of ultrasound examination suggested multiple enlarged lymph nodes in the bilateral neck, supraclavicular fossa, as well as axillary and inguinal regions, and CT examination of the abdomen showed multiple enlarged lymph nodes in the abdominal cavity, retroperitoneum, and bilateral inguinal regions. Because of the malignant lesions, after communicating with the patient, he agreed to undergo a lymph node biopsy to clarify the nature of the disease, and the results showed that it was a cellular lymphoma (immunoblastoid T-cell lymphoma), and because of the high degree of malignancy of the tumor, it was necessary to standardize the chemotherapy treatment in order to wait for the future effect. After the patient was admitted to the hospital, he was diagnosed as angioblastic immunoblastic T-cell lymphoma after completing various laboratory tests and lymph node biopsy, and was given CHOP chemotherapy after the diagnosis was clarified. After the diagnosis was confirmed, the patient was given CHOP chemotherapy, i.e., injectable cyclophosphamide, injectable epirubicin hydrochloride supplemented with injectable vincristine sulfate intravenously, and combined with oral prednisone acetate tablets for treatment. At the first chemotherapy session, the patient’s febrile symptoms improved significantly, indicating that the therapeutic drugs were effective. However, in the second chemotherapy, the patient experienced nausea and vomiting, which was considered to be the gastrointestinal adverse reaction caused by chemotherapeutic drugs, so the patient was given oral omeprazole enteric-coated capsule to protect the gastric mucosa, and ranitidine hydrochloride capsule to inhibit the secretion of gastric acid, and eliminate the symptoms. After treatment, the patient’s fever symptoms subsided significantly, and he reported that he had no other abnormal discomfort. Gastrointestinal discomfort appeared after the second chemotherapy treatment, and the gastrointestinal discomfort improved significantly after oral medication was given to the patient. The patient’s general condition was fine, no fever, no headache or dizziness, no chest tightness, no nausea or vomiting, no acid reflux or heartburn, no abdominal pain or diarrhea, diet and sleep were fine, bowel movement was normal, and the patient was instructed to return to the hospital for the next cycle of chemotherapy in 2 weeks, and then arranged to be discharged from the hospital to go home for recuperation. Fourth, precautions Because the patient’s body can tolerate chemotherapy drug treatment, two chemotherapy treatment effect is better, I sincerely feel happy for the patient, suggest that the patient’s daily attention to the following matters: 1, usually should pay attention to appropriate rest, develop a regular routine, and avoid heavy physical labor; 2, the daily diet should be strengthened nutrition, such as the intake of high-protein foods, such as milk, eggs, etc., should also increase the intake of vegetables and fruits, such as spinach, eggs, etc., and should also increase the intake of fruits, such as spinach, eggs, etc., and should also increase the intake of vegetables. Fruit intake, such as spinach, tomatoes, citrus, apples, etc.; 3, pay attention to the time of the next cycle of chemotherapy, and the day before the chemotherapy should return to the hospital for blood routine and liver and kidney function tests, to make clear whether there is any abnormality; 4, pay attention to warmth after discharge from the hospital, so as to avoid the decline of body resistance after chemotherapy treatment, and the cold invasion of cold induced cold. The patient in this case did not seek medical treatment in time after the fever symptoms appeared and did not undergo systematic examination, which led to the delay of the disease, making the treatment more difficult and the postoperative recovery time longer. However, the good thing is that the patient’s body can tolerate chemotherapy, so it is better to inhibit the progress of the disease, thus effectively prolonging the patient’s survival time. It is recommended that the general public should actively seek medical examination if symptoms of organic discomfort occur, so as to achieve early diagnosis and early treatment, so as not to aggravate the disease.