There are many clinical treatment modalities for gastrointestinal bleeding caused by portal hypertension and ruptured esophagogastric fundic veins in cirrhosis, but the clinical efficacy is not satisfactory. Interventional method for the treatment of portal hypertension is mostly applied in China through the internal jugular vein puncture intrahepatic portosystemic shunt (TIPS) to reduce portal hypertension and prevent and treat gastrointestinal bleeding; some scholars apply percutaneous hepatic percutaneous coronary vein embolization (PTVE) to eliminate the vessels responsible for bleeding, which can also achieve the effect of preventing and treating gastrointestinal bleeding. I. Technical methods: 1. Balloon blocking retrograde venous occlusion of varicose vessels Routine right femoral vein puncture to insert 6-8F guiding catheter to the opening of left renal vein, according to the measurement data of CTA scan, insert the corresponding size balloon catheter to the left adrenal vein via guidewire, fill the balloon to block the blood flow of left adrenal vein and perform varicose plexus imaging at the same time. According to the contrast dose required to completely fill the varicose plexus, the same dose of polyglactin foam is slowly injected for sclerotherapy (polyglactin foam is mixed with polyglactin, air, and iodophoresis in the ratio of 1:2:1 by mechanical aspiration), and the balloon is kept filled to maintain the contact of polyglactin with the intima for more than 30 minutes. Usually the morphological contour of the varicose plexus should match that shown by CTA, if it does not match, it indicates the presence of side branch drainage. In this case, according to the condition of the draining side branch, super-selective cannulation or direct injection of gelatin sponge pellets + anhydrous alcohol should be used to embolize the side branch before sclerotherapy of the varicose plexus; 2. Partial splenic artery embolization Partial splenic artery embolization should be performed at the same time if hypersplenism occurs. Gastroscopy was reviewed within 7-10 days after interventional catheterization, and polyglactin sclerotherapy was performed for cases with residual esophageal varices, and tissue gel (Cyanoacrylate) injection was performed for cases with residual gastric varices. Second, the efficacy of the surgery, 7-10 days after the operation of gastroscopy, all patients with varicose gastric veins obviously wrinkled, atrophied, the surface of the patchy or dark red, combined with the lower esophageal varices, 67% of patients with varicose veins disappeared, 25% of patients with varicose veins less than before, the local patchy changes, 8% of patients with varicose esophageal veins changes are not obvious, the latter two types of patients treated with endoscopic sclerotherapy. In 75% of the patients, the varices disappeared from the stomach and 92% of the patients had disappeared from the esophagus after gastroscopic review in one month. The CT enhancement was repeated in three months after the operation and showed that the esophageal and gastric varices had completely disappeared. All patients were followed up from 6 months to 42 months after surgery, and there was no rebleeding event. III. Summary The vascular embolization method for the treatment of esophagogastric varices and prevention of upper gastrointestinal bleeding requires corresponding therapeutic measures for different variceal types, focusing on the combined application of multiple techniques. On the one hand, the responsible vessels for bleeding should be eliminated to maintain adequate liver blood perfusion and protect liver function, and on the other hand, portal vein pressure should be appropriately reduced to reduce the occurrence of hepatic encephalopathy, and targeted treatment of underlying diseases is required.