Chest tightness caused by coronary heart disease can contain nitroglycerin, chest tightness caused by bronchospasm can be inhaled terbutaline, chest tightness caused by mental tension can be given sedation treatment, according to the specific conditions of the choice of symptomatic treatment. The common cause of chest tightness is coronary artery disease, myocardial ischemia can lead to chest tightness, rapid relief requires nitroglycerin, most patients will be relieved within 3~5 minutes. Chest tightness can also be seen in bronchial diseases, such as bronchial asthma, can be nebulized inhalation terbutaline, can relieve tracheal spasm, increase airway ventilation, relieve chest tightness symptoms. Chest tightness can also be seen in neurosis, may be related to excessive tension, can be given appropriate symptomatic drug treatment, such as oral diazepam. There are many causes of chest tightness, the symptoms are obvious, we should go to the hospital in time, under the guidance of the doctor for treatment.