(1) The treatment of Ménière’s disease by tympanic chamber injection of gentamicin is called ‘chemical vagotomy’ and is currently in the human trial stage. (2) Because it is a completely destructive treatment, in order to protect the health and interests of patients, doctors in regular hospitals in China and abroad should inform patients of the potential physical damage when treating them and go through the hospital medical ethics committee. (3) The answers that patients themselves have the right to know from their doctors are:1) How deaf am I now and do I still have hearing?2) Will I be totally deaf after the drug? 3) Will it affect my good ear?4) Will I still have tinnitus if I am totally deaf?5) Will I still have dizziness if I am totally deaf?6) Will it cause other problems besides total deafness?7) How many patients has this doctor treated with the same method and what are the results? (4) The challenge for the doctor is 1) Bilateral aural Meniere’s disease: Patients with unilateral aural Meniere’s disease rely on the opposite normal ear for compensatory regulation of homeostasis, what about the complete destruction of the function of the diseased ear and the reoccurrence of the normal ear? (2) Delayed membranous vagal effusion: After severe or total deafness in one ear, causing membranous vagal effusion in the inner ear, after total deafness in one ear, the other ear only hears sound and cannot distinguish words what to do? (5) At present, in the academic field of vertigo treatment, tympanic chamber injection of gentamicin for Meniere’s disease is a hot topic of debate among doctors. (6) At present, there is no indication in our national Pharmacopoeia that gentamicin can treat Ménière’s disease as an invasive treatment. The correct philosophy in the treatment of otologic diseases now is that the only way to preserve even residual hearing as much as possible is to preserve the function of the ear, leaving enough time for future breakthroughs in the treatment of inner ear diseases. Therefore, the choice of treatment for a patient must be made for the patient’s sake, and the doctor must be careful when choosing destructive treatments or treatments with long-term potential damage, so as to avoid giving the patient indiscriminate medication today and fighting with the patient tomorrow.