Warts are a viral skin disease caused by human papillomavirus (HPV) infection. Humans are the only hosts of HPV and it is mainly transmitted through direct contact, but trauma is also a major factor in causing infection. Warts infection is related to the immune function of the body, especially cellular immunity. Most warts are seen in children and young adults and include common warts, plantar warts, and flat warts. The vast majority of warts fade over time, but they can cause pain, affect aesthetics, and cause a lack of self-confidence. There is no specific antiviral therapy that can cure HPV infection, and the available therapies focus on either destroying and removing visible lesions or inducing a cytotoxic effect on infected cells. Treatment avoids the use of scarring treatments to remove warts whenever possible. Liquid nitrogen freezing is one of the most commonly used therapies, which can be followed by painful, occasionally blistering warts, and post-treatment hypopigmentation and hyperpigmentation. In addition, according to the lesion performance scraping, CO2 laser, pulsed dye laser, photodynamic therapy, local heat therapy can also be used. The actual topical application of drugs, such as 5% Imiquimod cream, 5% 5-fluorouracil ointment, 0.5% tincture of ghosts, 0.025 to 0.1% retinoic acid ointment, etc., can also be used topically. Corrosive drugs are mainly used for common warts or plantar warts, including 10% salicylic acid ointment, crystal ointment (containing 20% sodium hydroxide, etc.). Formaldehyde soaks the feet for 15 to 20 minutes every night. Pure Chinese herbal compound Icool skin disinfectant can also be applied. Systemic treatment can be used as an adjunctive therapy with oral levamisole, cimetidine, zinc sulfate, retinoic acid, etc.