Patients with gray nails have fungal infection of the nail plate area, resulting in the destruction of the structure of the nail plate itself, which causes the nails to turn yellow and thicken, and they tend to chip and fall off. The nails of people with gray nails are still growing after shedding, depending on the severity of the disease, commonly as follows: 1, continue to grow: most patients with gray nails will grow new nails after shedding, if the disease is not controlled, even if the new nails grow, it is possible that the diseased nails; 2, stop growing: full nail destruction type of gray nail patients nail shedding, because the entire nail plate is destroyed, the nail plate part or all off The nail structure is completely lost, and the nail matrix and nail bed are papilloma-like changes, when the nail matrix has been destroyed, usually can not grow new nails. When the patient’s nails appear lusterless gray spots and gradually turn yellowish brown to black, you should go to the hospital promptly and follow the doctor’s instructions to treat the disease by taking oral terbinafine, itraconazole, and applying topical terbinafine ointment and sertaconazole ointment. In severe cases, nail removal is required to avoid the development of full nail destruction, which can lead to nail loss and failure to grow back, affecting function and aesthetics.